
Serene Serum
Sensitive & Reactive Skin
Product expires November 2026 — grab it at a steep discount while supplies last
In stock! Ships within 1-2 business days.
Manufactured Here in the USA
Pharmacist-Formulated

Serene Serum
Product Details
A highly effective peptide-enriched daily serum and the top seller in the Serene line, a versatile option that may be suitable for all skin types and ages. Powered by three proprietary Defensil ingredients (Defensil-Plus, Defensil, and Defensil-Soft), this serum is designed to support a more comfortable-feeling skin barrier. Black Currant Seed Oil and Balloon Vine Extract help address the appearance of dryness and irritation while supporting a more comfortable-feeling complexion. Cucumber and Arnica Extracts help support hydration and a calmer-looking complexion. Acetyl Tetrapeptide-40 helps address the appearance of facial redness and supports a more even-looking skin tone. Sodium Hyaluronate provides a localized delivery system that keeps the serum where it's applied for targeted, comfortable support.
| Ingredient | What It Does |
|---|---|
| Defensil-Plus™ (Black Currant Seed Oil + Balloon Vine Extract + Sunflower Oil Concentrate) | A soothing complex designed for stressed and sensitive skin; helps calm the appearance of visible redness and irritation and supports a more comfortable, balanced skin feel |
| Defensil-Soft™ | A calming ingredient that helps soothe skin upon application and supports ongoing skin comfort, designed to help keep skin within its comfort zone |
| Cucumis Sativus (Cucumber) Fruit Extract | A naturally rich source of antioxidants and vitamins; hydrating, soothing, and cooling, helps support a refreshed, comfortable skin feel |
| Arnica Montana Flower Extract | A botanical extract that helps contribute to a calmer, more even-looking complexion. |
| Acetyl Tetrapeptide-40 | A peptide designed to help address the visible appearance of facial redness and support a more even-looking skin tone; may also help support the appearance of a firmer-feeling complexion over time |
| Sodium Hyaluronate | Deeply hydrating; its gelatinous texture helps keep the serum localized at the area of application, supports targeted, comfortable use |