a bottle of strive activate a butyrate generator for natural GLP-1 support containing 60 capsules

Activate by Strive - Butyrate Generator & GLP-1 Activator

$49.90
By Strive Pharmacy

Advanced Gut Health Designed to Activate GLP-1s Produced By The Body

Clinical Focus:

Activate is a cutting-edge dietary supplement designed to optimize gut health and metabolic function. With its innovative butyrate-generating formula and synergistic blend of key nutrients, Activate supports GLP-1 secretion1 by interacting with short-chain fatty acid (SCFA) receptors2, improving intestinal barrier integrity, reducing inflammation, and enhancing metabolic efficiency. It is particularly beneficial for individuals seeking weight management, glycemic control, and overall gut health.

Potential Benefits:

  • Promotes the generation of butyrate, key factor in GLP-1 activation.1,2
  • Supports a healthy gut microbiome and enhances intestinal barrier function.
  • Helps reduce oxidative stress and inflammation in the digestive tract.3
  • Aids in metabolic regulation, including glycemic control and insulin sensitivity.4
  • Protects the liver and intestinal barrier from toxins and bacterial insults.3,5,6
  • May contribute to weight management by improving energy metabolism.

Key Ingredients & Actions

  • ButyraGen™ (Tributyrin Complex) – Supports the generation of butyrate directly in the colon, providing sustained benefits. May enhance intestinal barrier integrity and reduce inflammation.
  • Calcium and Magnesium – Essential minerals that support digestive health and promote balanced gut microbiota.
  • Mixed Carotenoids (Vitamin A Source) – Provide antioxidant protection and support epithelial cell health.
  • Pantothenic Acid – Necessary for the synthesis of acetyl-CoA, supporting butyrate metabolism and energy production. 

How It Works3

Activate works by leveraging the unique properties of tributyrin, a highly bioavailable butyrate generator. Butyrate, a short-chain fatty acid, is critical for colon health and metabolic regulation. Its mechanisms include:

  • Enhancing Gut Health: Butyrate serves as the primary fuel for colonocytes, strengthening the intestinal barrier and reducing permeability.
  • Modulating Inflammation: By supporting the gut microbiome and reducing oxidative stress, butyrate decreases inflammation throughout the body.
  • Improving Metabolic Efficiency: Butyrate has been shown to enhance insulin sensitivity, regulate glucose metabolism, and reduce fat accumulation, contributing to overall metabolic health.

Why Choose Activate?

Activate provides a comprehensive solution for gut and metabolic health. Its innovative formulation focuses on generating butyrate, a key postbiotic with far-reaching benefits, from within the colon.3 Activate is particularly beneficial for those on GLP-1 therapies, aiming to enhance their metabolic and digestive outcomes by addressing gut-related symptoms like bloating and irregularity. Choose Activate to unlock the synergy between gut and metabolic health—because true wellness starts from the inside out.

Dietary Ingredients & Supplement Facts

Serving Size
 2 Capsules
Serving Per Container 30 1/2 Month Supply
Dietary Ingredients Amount per serving % Daily Value
Vitamin A (as natural mixed carotenoids and acetate) 975 mcg RAE 108%
Pantothenic Acid (as calcium pantothenate) 16.7 mg 334%
Calcium (as calcium citrate) 40 mg 3%
Magnesium (as magnesium citrate) 40 mg 10%
ButyraGen™ Tributyrin Complex 1,000 mg *

*Daily Value not established 

Other ingredients:

Capsule shell (gelatin and water), gum arabic, guar fiber, rosemary extract, silica and cellulose.

Suggested Dosing Directions

Two (2) capsules as a dietary supplement or as otherwise directed by a healthcare professional.

Reference

  1. van de Wouw, M., Boehme, M., et al. (2018). “Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations.” Journal of Physiology, 596(20), 4923–4944.
  2. Canfora, E. E., Jocken, J. W., & Blaak, E. E. (2015). “Short-chain fatty acids in control of body weight and insulin sensitivity.” Nature Reviews Endocrinology, 11(10), 577–591.
  3. ButyraGen Reduces Oxidative Stress Study.” NutriScience Innovations, LLC. Self-Published Technical White Paper. March 7, 2022.
  4. Depommier C, Everard A, Druart C, et al. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Nat Med. 2019 Jul;25(7):1096-1103.
  5. Miyoshi M, Sakaki H, Usami M, et al. Oral administration of tributyrin increases concentration of butyrate in the portal vein and prevents lipopolysaccharide-induced liver injury in rats. Clin Nutr. 2011 Apr;30(2):252-8.
  6. Miyoshi M, Usami M, Kajita A, et al. Effect of Oral Tributyrin Treatment on Lipid Mediator Profiles in Endotoxin-Induced Hepatic Injury. Kobe J Med Sci. 2020 Dec 16;66(4):E129-E138.
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